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Pentamethonium Dibromide

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Pentamethonium Dibromide Specification

Smell
Odourless

Usage
Mainly for laboratory, research, and pharmaceutical purposes

Taste
Bitter

Shelf Life
2 years if stored properly

Appearance
White crystalline powder

Physical Form
Powder

Product Type
Active Pharmaceutical Ingredient

Shape
Crystalline

Application
Ganglionic blocker, used in research and pharmaceutical formulations

Poisonous
YES

Structural Formula
[C11H26Br2N2]

Molecular Weight
362.15 g/mol

Melting Point
284-286 C (decomposition)

Properties
White or almost white crystalline powder, hygroscopic, odourless, soluble in water.

Purity
>=98%

Solubility
Soluble in water, slightly soluble in alcohol

Ingredients
Pentamethonium Dibromide

HS Code
29221990

Storage
Store in cool, dry, well-ventilated area away from light

EINECS No
200-303-0

Ph Level
Neutral (aqueous solution)

Density
1.38 Gram per cubic centimeter(g/cm3)

Molecular Formula
C11H26Br2N2

CAS No
56-94-0

Grade
Pharmaceutical Grade

Pentamethonium Dibromide Trade Information

Main Export Market(s)
Western Europe, Central America, Australia, North America, South America, Middle East, Eastern Europe, Asia, Africa

Main Domestic Market
All India

About Pentamethonium Dibromide

Pentamethonium dibromide is a medication that belongs to the class of drugs known as ganglionic blockers. It is used primarily in anesthesia as a muscle relaxant and to lower blood pressure during surgical procedures.

Pentamethonium dibromide works by blocking the activity of ganglionic nicotinic acetylcholine receptors in the autonomic nervous system. This causes a decrease in the activity of both the sympathetic and parasympathetic nervous systems, leading to a decrease in heart rate, blood pressure, and smooth muscle activity.

In addition to its use in anesthesia, pentamethonium dibromide has also been used in the treatment of hypertension, although it has largely been replaced by other medications with fewer side effects. It is not commonly used in clinical practice today.

Pentamethonium dibromide is administered intravenously and is rapidly metabolized and excreted by the kidneys. Side effects can include dry mouth, urinary retention, and decreased gastrointestinal motility. It can also cause a decrease in respiratory function and should be used with caution in patients with respiratory disease.

Overall, pentamethonium dibromide is a medication with a specific set of uses, primarily in anesthesia and as a treatment for hypertension. While it is effective in its intended applications, its side effects and potential for respiratory depression limit its use in clinical practice.

FAQ

1. Pentamethonium dibromide: What is it?

Ans - A cationic quaternary ammonium salt with the chemical formula (C5H11Br2)+ is pentamethonium dibromide. It is a colourless solid that can be dissolved in polar solvents like water.

2. How is pentamethonium dibromide structured?

Ans - Five carbon atoms, eleven hydrogen atoms grouped in a ring, and two bromine atoms bound to the carbon atoms make up pentamethonium dibromide.

3. For what purposes is pentamethonium dibromide used?

Ans - Pentamethonium dibromide is a surfactant that is employed in a number of formulations, a food preservative, an antiseptic in cosmetics, and a medicinal.

4. Is it safe to take pentamethonium dibromide?

Ans - When administered at approved dosages, pentamethonium dibromide is usually regarded as a safe substance. When handling the compound, personal protective equipment should be worn and caution should be exercised.

5. How is dibromopentamethonium stored?

Ans - Pentamethonium dibromide should be kept in a firmly closed container and kept in a cool, dry location. It should not be exposed to fire, flame, or harsh sunlight.

High Purity and Pharmaceutical Grade Quality

Pentamethonium Dibromide is supplied at a purity level of 98%, making it suitable for precise laboratory experiments and pharmaceutical research. Its crystalline, white, and nearly odorless form ensures consistent quality and ease of handling for researchers and manufacturers.

Safe Handling and Storage Recommendations

For optimal safety, handle Pentamethonium Dibromide using personal protective equipment and work in a well-ventilated area. The compound remains stable when stored in tightly sealed containers away from light, heat, and strong oxidizers, ensuring a shelf life of up to two years under recommended conditions.

Versatile Research and Pharmaceutical Applications

As a potent ganglionic blocker, Pentamethonium Dibromide is relied upon in various research settings. Its solubility in water and compatibility with multiple formulation processes make it valuable for pharmaceutical developments and laboratory investigations.

FAQs of Pentamethonium Dibromide:

Q: How should Pentamethonium Dibromide be safely handled in the laboratory?

A: Always use personal protective equipment, such as gloves, goggles, and lab coats, when handling Pentamethonium Dibromide. Avoid direct skin or eye contact, and ensure your workspace is well ventilated to minimize inhalation risks.

Q: What is the main application of Pentamethonium Dibromide?

A: Pentamethonium Dibromide is primarily used as a ganglionic blocker in research and the development of pharmaceutical formulations. It is suitable only for laboratory and research purposes, not for human or veterinary therapeutic use.

Q: When does Pentamethonium Dibromide decompose, and how should it be stored?

A: This compound decomposes before reaching its boiling point and should be stored in sealed containers, in a cool, dry, and well-ventilated area away from direct light and strong oxidizing agents. Proper storage helps maintain stability and extends shelf life up to two years.

Q: Where can Pentamethonium Dibromide be purchased and in what packaging?

A: You can obtain Pentamethonium Dibromide from exporters, manufacturers, and suppliers in India. It is available in sealed glass vials or polyethylene bottles to ensure product integrity during storage and transport.

Q: What are the first aid measures if exposure to Pentamethonium Dibromide occurs?

A: In case of skin or eye contact, immediately rinse the affected area thoroughly with water and seek medical attention. If inhaled or ingested, move to fresh air and call for medical help promptly.

Q: Is Pentamethonium Dibromide an environmental hazard?

A: While small laboratory quantities may not pose a significant threat, Pentamethonium Dibromide can be hazardous to the environment if released in large quantities. Always dispose of it according to local regulations, and prevent its release into natural waterways.

Q: What are the advantages of using this compound in research?

A: With high purity and a stable, soluble form, Pentamethonium Dibromide enables reliable experimentation in pharmacological and physiological studies. Its consistent quality supports accurate results in scientific investigations.

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