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Hexamethonium Dichloride

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Hexamethonium Dichloride Specification

Shelf Life
24 months

Product Type
Active Pharmaceutical Ingredient

Appearance
White crystalline powder

Properties
Quaternary ammonium compound; Water soluble; Stable under recommended storage conditions

EINECS No
200-469-3

Melting Point
280-282C (dec.)

Purity
>=99.0%

Application
Used as a ganglionic blocker in research and pharmaceutical formulations

CAS No
60-25-3

Ingredients
Hexamethonium Dichloride

Solubility
Soluble in water, slightly soluble in ethanol

Taste
Bitter

Shape
Crystalline

Storage
Store in a tightly closed container, in a cool, dry place, away from incompatible substances

HS Code
2921.19.90

Usage
Research and laboratory use; As a pharmaceutical intermediate

Poisonous
YES

Structural Formula
[H3C-(CH2)6-N+(CH3)2-CH2]Cl-

Molecular Weight
277.3 g/mol

Smell
Odorless

Molecular Formula
C12H30Cl2N2

Grade
Pharmaceutical Grade

Physical Form
Powder

Hexamethonium Dichloride Trade Information

Main Export Market(s)
Central America, Asia, North America, South America, Eastern Europe, Western Europe, Middle East, Australia, Africa

Main Domestic Market
All India

About Hexamethonium Dichloride

Hexamethonium dichloride is a quaternary ammonium compound that is composed of the cation hexamethonium and the anion chloride. With the chemical formula C₁₂H₃₀Cl₂N2, it is a white crystalline solid that is highly soluble in water. It is a ganglionic blocking agent that works by blocking the nicotinic acetylcholine receptors in autonomic ganglia, that decreases sympathetic and parasympathetic tone. Hexamethonium dichloride has been used as a pharmaceutical drug in the treatment of hypertension, but its use has declined due to the development of newer and more effective antihypertensive drugs. It is still used in research to study the physiological and pharmacological effects of ganglionic blockade.

FAQ

1. What is dichloride of hexamethonium?

Ans - The chemical formula for the organic compound hexamethonium dichloride is C6H12Cl2. It has a distinctive smell and is a solid white colour. It is employed in the creation of medications and as a pesticide.

2. What is the usage of hexamethonium dichloride?

Ans - Both in the manufacture of pharmaceuticals and as an insecticide, hexamethonium dichloride is employed.

3. What are the potential health hazards of hexamethonium dichloride?

Ans - Hexamethonium dichloride exposure can irritate the skin, eyes, and lungs. Additionally, it may result in headaches, nausea, dizziness, and impaired vision. Hexamethonium dichloride exposure over an extended period of time can harm the kidneys and liver.

4. In what manner should hexamethonium dichloride be kept?

Ans - Storage conditions for hexamethonium dichloride should be cool, dry, and aired. It should not be exposed to direct sunlight and should be kept away from heat and ignition sources.

5. How should hexamethonium dichloride spills be cleaned up?

Ans - Hexamethonium dichloride spills need to be cleaned up right away. Protective clothes, respirators, and the area should be aired and evacuated. With the use of a suitable absorbent substance, the spill should be confined and neutralised. The absorbent material should then be collected and disposed of as hazardous waste.

High Purity for Specialized Applications

Hexamethonium Dichloride offered here is pharmaceutical grade with a minimum purity of 99.0%. This high level of purity ensures reliability for research, laboratory, and pharmaceutical uses where consistency and performance are critical. Its stable, crystalline form supports safe storage and precise measurements in advanced applications.

Safe Handling and Storage

This compound remains stable at room temperature when stored in tightly closed containers, kept away from incompatible substances in a dry, cool place. It is non-flammable and not classified as dangerous for transport, making storage and handling straightforward for laboratories and manufacturers alike.

Versatile Packaging and Supply

Available in HDPE drums or custom packaging upon request, Hexamethonium Dichloride is distributed by an experienced supplier in India. Flexible packaging options cater to diverse research and industrial needs, ensuring product integrity during storage and transit.

FAQ's of Hexamethonium Dichloride:

Q: How should Hexamethonium Dichloride be stored to maintain its stability?

A: Store Hexamethonium Dichloride in a tightly closed container, placed in a cool, dry area, and keep it away from incompatible materials to ensure long-term stability. This protects its pharmaceutical-grade quality and prolongs its shelf life.

Q: What is the main usage of Hexamethonium Dichloride in research settings?

A: This compound is primarily used as a ganglionic blocker in pharmacological research and as an intermediate in pharmaceutical formulations. Its potency and reliability make it valuable for experimental and development work.

Q: When is Hexamethonium Dichloride considered safe for transport?

A: Hexamethonium Dichloride is not classified as hazardous for transport and does not possess a flash point, as it is non-flammable. It can be safely shipped under standard regulations using HDPE drums or other approved containers.

Q: Where can Hexamethonium Dichloride be sourced from?

A: Hexamethonium Dichloride can be sourced from established exporters, manufacturers, and suppliers in India, who provide verified pharmaceutical-grade material suitable for research and industrial applications.

Q: What is the benefit of using pharmaceutical-grade Hexamethonium Dichloride?

A: Pharmaceutical-grade Hexamethonium Dichloride, with 99.0% purity, assures consistency, safety, and effectiveness in research and pharmaceutical processes, supporting precise and reproducible results.

Q: How is Hexamethonium Dichloride commonly packaged for delivery?

A: This product is typically supplied in HDPE drums to ensure safe handling and storage. Custom packaging solutions are also available to meet specific client requirements and regulatory standards.

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